Go to www.wellsfargo.com/activate to quickly and safely activate your Wells Fargo card through the 3 step process, or through a local ATM in your area. Learn how to activate new Wells Fargo debit card here, as you can activate your new debit card online, through phone, and as well at any Wells Fargo ATM. For your security we do not recommend using this feature on a shared device. End of popup. Welcome Online & Mobile Security. New to Wells Fargo Online. Follow the easy process below to activate your new Wells Fargo Debit Card online: Visit wellsfargo.com/activatecard. Next, type in your Wells Fargo Online username and password; Then click “Sign On” to proceed. Now, kindly select the card you would like to activate and follow the instructions to complete the activation process. Installation Package Netfx Msi.